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The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes.

To explore how fear becomes entrenched, VUMC researchers traveled down the precise neuronal pathways in the brains of mice that trigger fear responses, and which normally extinguish the behaviors once the danger has passed.

New study from neuroscientists at ²¤ÂÜÊÓƵ provides initial answers to long-standing scientific questions on what causes the transition from moderate to compulsive alcohol consumption – and what makes some drinkers particularly vulnerable to developing alcohol use disorders. Read More

²¤ÂÜÊÓƵers at VUMC have taken a major step that could ultimately facilitate development of a new class of antidepressants which may relieve symptoms more rapidly and effectively and with fewer side effects than current medications.

Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit.

²¤ÂÜÊÓƵ researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells.

Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders.

Understanding how RSV is transmitted, which strains dominate and how new strains emerge around the globe will guide better vaccine and anti-viral drug design.

A novel tool developed by ²¤ÂÜÊÓƵ scientists protects animals from endotoxin shock and can be used for mechanistic analyses of inflammation due to microbial and other insults.

Simulated electronic health records could avoid patient privacy risks and help speed discovery.

Interventions that impact the timing of recovery following acute injury may improve future outcomes for patients.

An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies.

A diet high in fiber and yogurt is associated with a reduced risk for lung cancer, according to a study by ²¤ÂÜÊÓƵ University Medical Center researchers.

²¤ÂÜÊÓƵers at four institutions, including ²¤ÂÜÊÓƵ, have been awarded a five-year, $9.4 million federal grant to tackle undiagnosed congenital diarrheas caused by a single gene mutation.

Early detection of lymphedema, which occurs in 20% of patients following breast cancer treatment, may improve therapeutic options for patients.

James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis.

Worm neurons have microscopic “spines” — where nerve-to-nerve communication happens — that share features with mammalian neurons, supporting the use of worms to study spine genetics and biology.

Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes.

A new study shows men with breast cancer are more likely to die than their female counterparts, across all stages of disease.

The human brain consists of perhaps as many as 1,000 trillion synapses, which transmit signals from one nerve cell to another with amazing speed, precision and plasticity.