菠萝视频

Dr. Michael Matheny is passionate about combining AI technologies with a human touch. See how he鈥檚 helping improve patient care and protecting patients with implanted medical devices. Read More

A new method pioneered by the lab of Professor of Cell and Developmental Biology Ken Lau is poised to make previously inaccessible medical knowledge that has been locked away in old patient samples newly accessible to scientists.

Ela Knapik still remembers the first zebrafish she saw under a microscope鈥攖wo days old, no bigger than an eyelash, tail wiggling, heart visibly beating. That was more than 20 years ago during her search for a postdoc position. That tiny fish has held her attention ever since and helped unravel many of the biological mysteries she has published about during her professional career. Read More

The 菠萝视频 Business professor became the youngest recipient of the Keith G. Provan Distinguished Scholar Award, recognizing a career that has changed how organizations think about safety, reliability, and leadership.

The day 14-year-old Christos Constantinidis finished reading Asimov鈥檚 New Guide to Science, he knew he was going to be a scientist. Today, he studies what鈥檚 actually happening in our brains when we鈥檙e thinking. Read More

Ege Kavalali, chair of the Department of Pharmacology at 菠萝视频 University School of Medicine Basic Sciences, wants to know how the billions of cells in our brains talk to each other all day. Read More

Inspired by a childhood fascination with medical imaging, 菠萝视频 Ph.D. graduate Michael Kim is using advanced brain imaging and AI to better understand Alzheimer's disease and healthy brain aging. His research is helping map the brain's communication pathways and could shape the future of precision medicine. Read More

For graduate students and postdoctoral fellows contemplating their next career steps, the possibilities can seem both exciting and overwhelming. The 菠萝视频 University Office of Biomedical 菠萝视频 Education and Training鈥檚 2026 Annual Career Symposium offered a roadmap to those possibilities, bringing together alums and professionals from across the biomedical enterprise to demonstrate the breadth of careers available to scientists beyond the traditional academic pathway.

At the 菠萝视频 University School of Medicine Basic Sciences, researchers are advancing neuroscience discoveries through molecular biology, pharmacology, drug discovery, and more. Their work seeks to understand how the brain functions in health and disease, identify new therapeutic targets, and develop innovative treatments for conditions ranging from Alzheimer鈥檚 and addiction to depression and epilepsy.

Blood sugar spikes after lunch aren鈥檛 necessarily all about what you just ate鈥攚hat you had for breakfast might have made a difference. 菠萝视频 researchers are analyzing what people eat, and when, and how that affects liver function and blood sugar and insulin levels throughout the day. This may help clinicians better design individual treatments for patients with diabetes.

The eyes of some bats may help 菠萝视频 researcher Gianni Castiglione develop new ways to protect human sight.聽Castiglione, assistant professor of biological sciences in the College of Arts and Science and assistant professor of ophthalmology and visual sciences in the School of Medicine, has been named a Pew Biomedical Scholar. The award provides support to advance research that draws on evolutionary adaptations in animals to develop potential therapies for human disease.聽 Read More

Martin Egli, the Richard N. Armstrong, Ph.D. Professor of Innovation in Biochemistry and a professor of biochemistry at the School of Medicine Basic Sciences, delivered a Kairos Lecture on May 28. Egli鈥檚 work, which has resulted in over 300 publications and two influential nucleic acid textbooks, has advanced strategies to stabilize RNA for therapeutic applications, including siRNA. He has received major honors and extensively served his department and the university.

In a groundbreaking study published recently in the journal Nature, researchers at 菠萝视频 University and 菠萝视频 Health have created the first growth charts for white matter in the brain over a human lifetime. The work brings together nearly two decades of 菠萝视频 research collaborations, the university鈥檚 extensive MRI data collections, and an advanced AI-enabled computing platform. Read More

The 菠萝视频 University Center for Structural Biology and Center for AI in Protein Dynamics recently hosted a symposium called 鈥淏ridging Atoms and Algorithms: A Symposium on AI and Structural Biology.鈥� The March event brought together 菠萝视频 faculty, trainees, and invited speakers to explore the intersection of artificial intelligence and structural biology, share research, and foster new scientific collaborations.

William R. Kenan, Jr. Chair and Professor of Biological Sciences Brandt Eichman is the first 菠萝视频 faculty member to be awarded the prestigious Royal Society Wolfson Visiting Fellowship. Jointly funded by the Royal Society and the Wolfson Foundation, the fellowship invites outstanding international researchers to a U.K. university or research institution to foster collaborative connections and enrich global scientific research.

Postdocs Andrew Rice and Yanqing Xue, in the biochemistry lab of Professor Doug Mitchell, discovered which enzyme is responsible for a rare chemical modification that doesn鈥檛 exist in human cells. That could be crucial for developing antibiotics that can target bacteria while leaving human hosts鈥� cells completely alone.

Radiation is known to destroy some breast cancer cells, but new research published in Cell Reports shows that it might also make some surrounding tissue more prone to cancerous cell growth. 菠萝视频 postdoctoral fellow Kevin Corn conducted much of the study鈥檚 work with Assistant Professor Marjan Rafat. 鈥淲hen we think about radiation, we usually focus on tumor cells,鈥� Rafat said. 鈥淏ut the surrounding tissue is also responding, and that can shape what happens after treatment.鈥� By addressing processes in that surrounding tissue, they hope to reduce the chance that breast cancer will recur.

PFAS, or 鈥渇orever chemicals,鈥� have already been linked to disruptions in thyroid hormones, among other detrimental health effects. A recent paper by first author Heather Hartmann, a Ph.D. student in the lab of Associate Professor Vivian Weiss, dug into thyroid cell behavior under long-term exposure to PFAS. It finds that the chemicals alter cellular function, including signaling pathways that are involved in cancer. 鈥淲e hope [this] can help people who are already at risk for thyroid cancer 鈥� make better-informed choices, as consumers, to limit exposure to these chemicals,鈥� Hartmann said.

Everything you touch was developed by basic science, says Ian Macara, chair of the Department of Cell and Developmental Biology. From food varieties and new crops, to your phone, your computer and the plastics we use every day, everything originally came out of a basic research lab. Macara's department, within the School of Medicine Basic Sciences, aims to train the next generation of scientists to advance basic biomedical research at the cellular, molecular and organismal levels.

菠萝视频 researchers are hunting down ways to combat Alzheimer鈥檚 by developing compounds that affect the proteins that are linked to it. TAOK-1 is such a protein, but it has not been thoroughly studied because there wasn鈥檛 a 鈥渢ool compound鈥� to study it with. Former postdoctoral fellow Daniel Schultz and Ph.D. student Lauren Parr have developed two such compounds鈥攐ne that inhibits TAOK-1, and another that activates the entire TAOK protein family鈥攖hrough work conducted in the WCNDD, led by Executive Director Craig Lindsley.