Health And Medicine
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The yin and yang of COX-2
New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs. Read MoreOct 2, 2015
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Major grant to transform region鈥檚 clinical practices
菠萝视频 University has received a contract from the Centers for Medicare and Medicaid Services (CMS) for up to $28 million over four years to help more than 4,000 clinicians in the Southeast transform their clinical practices in ways that improve quality of patient care and hold down costs. Read MoreOct 1, 2015
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Collaboration seeks to develop new therapies for bone, other diseases
La Jolla Pharmaceutical Co. and 菠萝视频 University have signed a research and license agreement covering 菠萝视频鈥檚 research program and intellectual property rights related to compounds that block bone morphogenetic protein (BMP) type-I receptors. The compounds have therapeutic potential in a broad range of diseases, including rare genetic disorders. Read MoreOct 1, 2015
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Tolerating a transplant
A new genetic model has generated new strategies for promoting tolerance to transplants 鈥 and improving long-term transplant outcomes 鈥 in the background of autoimmune disease. Read MoreOct 1, 2015
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Study shows decline in opioid use among preoperative patients
Declining use of prescription painkillers among preoperative patients seeking joint replacements indicates efforts by the state of Tennessee to tighten the spigot on opioids are beginning to have an impact, according to a study by 菠萝视频鈥檚 Andrew Shinar, M.D. Read MoreOct 1, 2015
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Reduced-nicotine cigarettes decreased dependence and frequency of smoking: NEJM study
Reduced-nicotine cigarettes were beneficial in reducing nicotine exposure and dependence, and also the number of cigarettes smoked per day, when compared with standard-nicotine cigarettes in a six-week study published in the New England Journal of Medicine. Read MoreSep 30, 2015
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Theatre program benefits children with autism:鈥坰tudy
Children with autism who participated in a 10-week, 40-hour, theatre-based program showed significant differences in social ability compared to a group of children with autism who did not participate, according to a 菠萝视频 study published in the Journal of Autism and Developmental Disorders. Read MoreSep 30, 2015
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Study tracks brain鈥檚 trigger for overeating high-fat food
Disruptions in a specific signaling pathway in the brain can cause overeating of high-fat food, researchers at 菠萝视频 University have found. Read MoreSep 24, 2015
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Survivors of Ebola outbreak take part in VUMC鈥坴accine study
Two survivors of a 2014 Ebola outbreak in Nigeria visited 菠萝视频 University Medical Center last week to share their experiences and participate in a study aimed at finding ways to treat the often-fatal infection. Read MoreSep 24, 2015
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Data diving for health
To most effectively use electronic health records for research, investigators should query multiple components of the record to identify patients with specific diseases. Read MoreSep 23, 2015
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Keep your coat on, virus!
A compound acting on serotonin receptors delays a critical step during reovirus cell entry, reducing viral infectivity. Read MoreSep 22, 2015
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Nerve cell remodelers
菠萝视频 investigators have defined a gene expression program that controls the timing of synaptic remodeling 鈥 a process that is critical to brain development, learning and memory. Read MoreSep 18, 2015
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Heart repair factor
A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack. Read MoreSep 17, 2015
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Study shows lower systolic BP targets reduce death risk
The initial results of a landmark clinical trial sponsored by the National Institutes of Health (NIH) indicate lowering systolic blood pressure below a commonly recommended target significantly reduces rates of cardiovascular events and lowers risk of death in a group of adults 50 years and older. Read MoreSep 17, 2015
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菠萝视频 Kennedy Center to continue as national Developmental Disabilities 菠萝视频 Center
The 菠萝视频 Kennedy Center (VKC) has been awarded a $6.5 million, five-year grant to continue as a national Eunice Kennedy Shriver Intellectual and Developmental Disabilities 菠萝视频 Center (IDDRC). Read MoreSep 17, 2015
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Grants spur effort to add genetic data to EMR
菠萝视频 University researchers have received two major federal grants 鈥 totaling $7.6 million over four years 鈥 to support groundbreaking research aimed at making genetic information a routine part of patients鈥 electronic medical records. Read MoreSep 10, 2015
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Diabetes trial targets body鈥檚 ability to produce insulin
Kiersten Eaddy had long looked forward to her high school graduation day and joining her classmates to celebrate the accomplishment. Read MoreSep 10, 2015
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Initiative seeks to bolster 鈥榬ediscovery research鈥
The 菠萝视频 Institute for Clinical and Translational 菠萝视频 (VICTR) is partnering with a public charity, Cures Within Reach, to encourage 鈥渞ediscovery research,鈥 the 鈥渞epurposing鈥 of already approved medical treatments to other conditions or diseases for which there are no 鈥渦niversally鈥 effective therapies. Read MoreSep 10, 2015
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Gifford, Bell land development awards in aging research
Two faculty members of the 菠萝视频 Memory and Alzheimer鈥檚 Center are among a handful of 2015 scholars for the Paul B. Beeson Career Development Awards in Aging 菠萝视频 Program. Read MoreSep 10, 2015
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Ebola symposium to feature Nigerian physicians
Three Nigerian physicians who survived Ebola virus disease in July 2014 after coming in direct contact with an Ebola-infected patient will speak at 菠萝视频 University Medical Center next Wednesday, Sept. 16. Read MoreSep 10, 2015