Health And Medicine
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PET imaging to predict tumor response
A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models. Read MoreJun 14, 2017
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Drug developed for arthritis could be first to stop heart valve calcification
The first drug to treat calcification of heart valves may be one originally designed for rheumatoid arthritis. Read MoreJun 12, 2017
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Repriming replication roadblocks
New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away. Read MoreJun 12, 2017
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Flip side of gut protection
²¤ÂÜÊÓÆµ investigators report that dysregulation of certain immune cells in the intestines may lead to inflammation and disease. Read MoreJun 9, 2017
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NIDDK renews ²¤ÂÜÊÓÆµâ€™s diabetes research grant
The ²¤ÂÜÊÓÆµ Diabetes ²¤ÂÜÊÓÆµ and Training Center (VDRTC) is celebrating its 44th year of operation with a five-year competitive renewal of its $9 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH). Read MoreJun 8, 2017
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²¤ÂÜÊÓÆµ-led study disputes link between uterine fibroids and miscarriage risk
A 10-year study, led by ²¤ÂÜÊÓÆµ University Medical Center professor of Obstetrics and Gynecology Katherine Hartmann, M.D., Ph.D., disrupts conventional wisdom that uterine fibroids cause miscarriages. Read MoreJun 7, 2017
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Forum highlights innovative approaches to bolstering biomedical research
How can we — together — make research at ²¤ÂÜÊÓÆµ University Medical Center (VUMC) better and stronger? Read MoreJun 1, 2017
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Preserving NIH’s Fogarty International Center crucial for global health efforts
This week Douglas Heimburger, M.D., M.S., professor of Medicine at ²¤ÂÜÊÓÆµ, joined a growing chorus calling for preservation of the Fogarty International Center of the National Institutes of Health (NIH). Read MoreMay 26, 2017
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²¤ÂÜÊÓÆµ delves into mental states of self-transcendent experiences
²¤ÂÜÊÓÆµers have, for the first time, described the similarity of different self-transcendent experiences — mental states that range from being in love to spiritual enlightenment — along a common continuum and spectrum of intensity. Read MoreMay 25, 2017
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Study reveals role for stem cells in chronic lung diseases
A novel population of lung stem cells plays an important role in regulating the pulmonary microvasculature — the network of tiny blood vessels where oxygen and carbon dioxide exchange takes place. Read MoreMay 25, 2017
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Oxidative stress in tumors
²¤ÂÜÊÓÆµ investigators have developed a new method for measuring oxidative stress in human tumors, which provides insight into cancer development. Read MoreMay 18, 2017
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Blood type link to cancer survival
Blood type A was associated with longer ovarian cancer survival in a recent ²¤ÂÜÊÓÆµ-led study. Read MoreMay 17, 2017
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RSV-HRV viral interference
RSV infection reduces the risk of infection with human rhinovirus, which could have implications for vaccine development and prevention strategies for viral respiratory tract infections in infants. Read MoreMay 15, 2017
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EETs contribute to insulin sensitivity
Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension. Read MoreMay 11, 2017
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Study finds male infants at increased risk for NAS
Male infants are more likely at birth than their female counterparts to be diagnosed with drug withdrawal symptoms, also known as neonatal abstinence syndrome (NAS), and to require treatment, according to a new ²¤ÂÜÊÓÆµ study published in Hospital Pediatrics. Read MoreMay 4, 2017
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Study seeks to reverse precancerous stomach lesions
²¤ÂÜÊÓÆµ University Medical Center cancer researcher James Goldenring, M.D., Ph.D., has received a two-year, $200,000 grant from the DeGregorio Family Foundation in Pleasantville, New York, to begin clinical trials of a potential approach for reversing precancerous stomach lesions. Read MoreMay 4, 2017
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New cell model to help test reproductive disease therapies
Kevin Osteen, Ph.D., Pierre Soupart Professor Obstetrics and Gynecology, and his team at the Women’s Reproductive Health ²¤ÂÜÊÓÆµ Center have developed a three-dimensional organ-on-a-chip cell model that mimics the endometrial lining of the uterus in an effort to test therapeutic interventions for reproductive diseases. Read MoreMay 4, 2017
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Therapeutic targets for diabetes
²¤ÂÜÊÓÆµ investigators have identified novel regulators of insulin-producing beta-cell proliferation and survival, suggesting new targets for the treatment of type 2 diabetes. Read MoreMay 3, 2017
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Clue to recurrent C. diff infection
Children who experience recurrent C. diff infections may have fecal inflammatory markers that could predict risk and improve management of these infections. Read MoreMay 1, 2017
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Regulating anxiety in the brain
Two brain signaling pathways have overlapping functions in regulating anxiety, suggesting that therapeutics aimed at one or the other will impact both. Read MoreApr 28, 2017