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Integrin-linked kinase, a central component of a complex that coordinates cell signaling involved in migration, proliferation and cell death, plays a role in kidney development and epithelial cell function.

Charles Sanders, PhD, and colleagues show how a “supertrafficking” mutant potassium channel contributes to heart rhythm abnormalities.

Cancer specialists at ������Ƶ University Medical Center, in partnership with biochemists and structural biologists across the ������Ƶ University campus, are taking “personalized” cancer therapy to a new level.

Tumors consume glucose at high rates, but a team of ������Ƶ researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

Unique somatic gene mutations may contribute to racial disparities in the incidence of Wilms tumor — the most common childhood kidney cancer.

������Ƶ researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine.

Team members serving COVID-19 inpatients were more densely connected, interacting far more than their medical ICU counterparts.

The discovery of monoclonal antibodies that neutralize Rift Valley Fever Virus — an emerging infection with pandemic potential — lays the foundation for future therapeutic antibody development.

Despite an impressive vaccination effort that exceeds 2 million shots a day, rates of COVID-19 are again on the rise in several parts of the United States, as is the spread of highly transmissible variants of the virus.

������Ƶ’s Muktar Aliyu, MBBS, MPH, DrPH, and Hilary Tindle, MD, MPH, will be inducted this year into the American Society for Clinical Investigation (ASCI), an elite honor society of physician-scientists from the upper ranks of academic medicine and industry.

Behavioral science research from Jennifer Trueblood, associate professor of psychology, identifies the best way to convince people to get vaccinated against SARS-CoV-2. Read More

Richard Tsien, PhD, director of the Neuroscience Institute at NYU Langone Medical Center, will deliver the next web-based Discovery Lecture.

������Ƶ snapshot: Study shows promise to bring back strain-relieving wearable tech to last-mile delivery drivers, heavy-lifting jobs and other essential workers, including those strained during pandemic.  Est. reading time: 1.5 minutes Read More

An FDA-approved medication enhances the function of T regulatory cells (Treg), a class of immune cells that restrains the immune response, ������Ƶ investigators have discovered.

Distinct cancer-associated fibroblasts in the prostate tumor microenvironment may influence tumor progression and could point to new therapeutic targets.

Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people.

High-intensity strength training is not more effective than low-intensity training or educational efforts for reducing knee pain in patients with osteoarthritis.

In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes.

������Ƶ University Medical Center is recruiting volunteers for a randomized controlled phase 2 clinical trial to help determine the prevalence of systemic allergic reactions (SARS) to the two-dose COVID-19 mRNA vaccines made by Pfizer-BioNTech and Moderna.

The U.S. Preventive Services Task Force (USPSTF) has formally recommended two changes that will nearly double the number of people eligible for lung cancer screening by lowering the age from 55 to 50 and reducing the number of smoking history pack years from 30 to 20.